Research Goal

The objective of this research is to develop a new, rapid method of amplifying DNA using polymerase chain reactions (PCR).  The PCR chip uses a new micro-nanofluidic device is based on the molecular gate, in which multiple types of gates are integrated with PCR  reaction chambers to enhance amplification rates, as well as a separation system with electronics and optical systems for detection of completed DNA structures. The device and approach includes on-chip heating and cooling,  incorporating advances in biomolecular tagging and recognizing a multiplicity of compounds, making on-chip analysis of the wide range of biological warfare agents a practical reality.  (IITR and Cbana)

Research Team:

Acknowledgement:

Work partially supported by NSF Nanoscale Science and Engineering Center Grant #

Related Publications: